Certified Clinical Research Associate (CCRA) Practice Exam 2025 – Complete Preparation Guide

In Phase 2 studies, the typical participant range is generally a few hundred individuals. The primary purpose of Phase 2 trials is to evaluate the efficacy of a drug or treatment and to further assess its safety, often focusing on a specific condition or disease. Conducting these studies with a larger participant group, usually between 100 and 300, allows researchers to collect more robust data regarding the treatment's effectiveness while still maintaining a manageable size for logistical and regulatory considerations.

This range of participants is crucial as it enables a better understanding of how the treatment performs in a more diverse population, which can help identify potential responses and side effects that may not have been evident in the smaller Phase 1 trials. An adequate number of participants can improve the statistical power of the results, allowing researchers to make more informed decisions about moving forward in the clinical development process.